1)Articles and books

 1.Yuhui Li#, Xuan Zheng#, Dan Li, Mingyang Sun, Zhuo Wang, Jingwu Li* and Yufeng Li*. Facilitation of Temozolomide Resistance of Glioblastoma by Long Noncoding RNA DLK1-35. Iranian Red Crescent Medical Journal. 2023 May; 25(5):e2468.

    2.Yuhui Li#, Xuan Zheng#, Jangong Wang, Mingyang Sun, Dan Li, Zhuo Wang, Jingwu Li*, Yufeng Li*, Yongliang Liu*. Exosomal circ-AHCY promotes glioblastoma cell growth via Wnt/β-catenin signaling pathway. Ann Clin Transl Neurol. 2023 Jun;10(6):865-878.

    3.Shuqing Wang#, Yufeng Li#, Yudong Zhang, Dan Li, Zhuo Wang, Yanrong Zhang, Ning Zhang, Jinghua Zhang*. Effect of JMJD6 and EYA2 on modulating radio-resistance of breast cancer cells. International Journal of Human Genentics. 2023, 23(1):75-84.

    4.Yuhui Li#, Dan Li#, Yankun Liu, Shuqing Wang, Mingyang Sun, Zhongyuan Zhang, Xuan Zheng, Jingwu Li*, Yufeng Li*. The positive feedback loop of NHE1-ERK phosphorylation mediated by BRAFV600E mutation contributes to tumorigenesis and development of glioblastoma. BBRC. 2022 Jan 15;588:1-7.

5.Cao X K,Ma Q H,Wang B,Qian Q Q,Xi Y N.Circ-E2F3 promotes cervical cancer progression by inhibiting microRNA-296-5p and increasing STAT3 nuclear translocation.[J] Ann N Y Acad Sci. 2021.

6.Qian Q Z,Ma Q H,Wang B,Qian Q Q,Zhao C S,Feng F M,Dong X N.MicroRNA-205-5p targets E2F1 to promote autophagy and inhibit pulmonary fibrosis in silicosis through impairing SKP2-mediated Beclin1 ubiquitination[ J ]Cell Mol Med.2021.

7.Wang p,Zhao X Q,Wu X T,Tang G S,Yuan L N.miR-15b-3p promotes the malignant progression of endometrial cancer cells through targeting KLF2[J] Cell Cycle.2021.20(14).1431-1440.

8.Xiong w,Huang X Z,Yao S H,Wang L Q,Wang J,Wang X H.Expression of AKR1C3,beta-Catenin and LEE1in Esophageal Squamous Call Carcinoma and the Relationship with Radiation Resistance[J] Iran J Public Health.2021,50(7).1488-1490

9.Zhang S L,Wang Y Q,Zhang J H,Hu J W,Ma J,Gu Z,Wang Y,Chen J J.Methylated p16 gene is associated with negative expression of estrogen receptor progesterone receptor and human epidermal growth factor receptor 2 in breast cancer[J] J Cancer Res Ther.2021,42(3),530-536

10.Li Y H,Zhou Y,Liu Y Y,Zhang G J,Xiao L,Li N,Qin H F,Wang J G,Zhang L.Severe immune-related hyperthermia followed by immune-related pneumonitis with PD-1 inhibitor (sintilimab) in small cell lung cancer:A case report[J] Case Reports.2021,12(11),1780-1783.

11.Xiong W,nHuang X Z,Hue W N.AKR1C3 and beta-catenin expression in non-small cell lung cancer and relationship with radiation resistance[J] J BUON.2021,26(3),802-811.

12.Zhang S Y,Ding X G,Miao H X,Wang L,Xian L G,Han S G,Zhang D,Li J.The Effects of MIR-320 on the Proliferation and Differentiation of Human Alveolar Bone-Derived Mesenchymal Stem Cells.2021,11(5),937-942.

13.Dai S,Huang Y,Liu T,Xu Z H,Liu T,Chen L,Wang Z W,Lou F.Development and validation of RNA binding protein-applied prediction model for gastric cancer[J]Aging(Albany NY).2021,13(4),5539-5552.

14.Zhao F C,Wang Z Y,Gao Y L,Wu Y S,Liu J M,He S L.Randomized Efficacy Trial of Conventional,TCM Herb,and TEAS onBone Marrow Suppression in Patients with Small Cell Lung Cancer after lnitial Chemotherapy[J] Evid Based Complement Alternat Med.2021,2021

15.Dong W Y,An B,Wang Y,CuiX Y,Gan J H.Effect of multimodal analgesia on gynecological cancer patients after radical resection[J] Am J Transl Res.2021,13(4)2686-2693.

16.Zhao J,Chai G Z,Yang F J,Xu L Z,Zhao J,Wang Y P,Liu C Y.Analysis of the change of clinical nursing pathway in health education among patients with ovarian carcinoma[J] Am J Transl Res.2021,13(4),3138-3146.

17.Dong W,Li J W,Dong X L,Shi W J,Zhang Y,Liu Y L.MiR-17 and miR-93Promote Tumor Progressio by Targeting p21 in Patients with Chordoma[J] Onco Targets Ther.2021,14,3109-3118.

18.Li Q K, Chen J, Hu Y, Höti N, Lih TM, Thomas SN, Chen L, Roy S, Meeker A, Shah P, Chen L, Bova GS, Zhang B, Zhang H. Proteomic characterization of primary and metastatic prostate cancer reveals reduced proteinase activity in aggressive tumors. Sci Rep[J] Sci Rep. 2021 Sep 23;11(1):18936.

19.Wang J#, Liu Y T#, Li Y, Zheng X, Gan J H, Wan Z Y, Zhang J, Liu Y, Wang Y Q, Hu W N*, Li Y F*, Liu Y K* Exosomal-miR-10a Derived from Colorectal Cancer Cells Suppresses Migration of Human Lung Fibroblasts and Expression of IL-6, IL-8 and IL-1β[J]. Molecular Medicine Reports. 2020 Accepted.

20.Liu Y, Zhang Y Y, Wang S Q, Li M, Long Y H, Li Y F*, Liu Y K, Li Y H, Wang Y Q, Mi J S, Yu C H, Li D Y, Zhang J H*, Zhang X J*. WSTF acetylation by MOF promotes WSTF activities and oncogenic functions[J]. Oncogene. 2020(39):5056-5067.

21.Liu Y, Long Y H, Wang S Q, Zhang Y Y, Li Y F, Mi J S, Yu C H, Li D Y, Zhang J H*, Zhang X Z*. JMJD6 regulates histone H2A.X phosphorylation and promotes autophagy in triple-negative breast cancer cells via a novel tyrosine kinase activity[J]. Oncogene. 2019,38(7):980-997.

22.Xiao J#, Liu Y K#, Wu F X #,Liu R Y#, Xie Y L, Yang Q, Li Y F, Liu M, Li S P, Tang H*. miR-639 Expression Is Silenced by DNMT3AMediated Hypermethylation and Functions as a Tumor Suppressor in Liver Cancer Cells[J]. Molecular Therapy. 2020 Feb 5;28(2):587-598.

23.Hu Y, Wu F X, Liu Y K, Zhao Q, Tang H*. DNMT1 Recruited by EZH2-mediated Silencing of miR-484 Contributes to the Malignancy of Cervical Cancer Cells Through MMP14 and HNF1A[J]. Clinical Epigenetics. 2019,11:186.

24.Yao L L, Zhou Y D, Sui Z H, Zhang Y L, Liu Y K, Xie H, Gao H J, Fan H X, Zhang Y, Liu M, Li S P, and Tang H. HBV-encoded miR-2 functions as an oncogene by downregulating TRIM35 but upregulating RAN in liver cancer cells[J]. EBioMedicine. 2019 Oct;48:117-129.

25.Liu Y, Long Y H, Wang S Q, Zhang Y Y, Li Y F, Mi J S, Yu C H, Li D Y, Zhang* J H, Zhang* X J. JMJD6 regulates histone H2A.X phosphorylation and promotes autophagy in triple-negative breast cancer cells via a novel tyrosine kinase activity[J]. Oncogene, 2018, 38(7):980-997.

26.Li Y F, Dong W Y, Shan X J, Hong H, Liu Y, Liu Y K, Liu S H, Zhang* X J, Zhang* J H. Anti-tumor effects of Mfn2 in breast cancer are promoter DNA methylation, P21Ras binding site and PKA phosphorylation site dependent[J]. Oncology Letters, 2018, 15(5):8011-8018.

27.Dong W, Li J, Liu Q, Liu C, Li C, Song G, Zhu H, Gao H, Zhang Y. P21waf1/cip1 and p27kip1 are correlated with the development and invasion of prolactinoma[J]. Journal of Neuro-Oncology, 2018, 136(3):485-494.

28.Liu M Y, Zhang Y, Zhang J, Cai H, Zhang C, Yang Z, Niu Y, Wang H, Wei X, Wang W, Gao P, Li H, Zhang J H, Sun G H. MicroRNA-1253 suppresses cellproliferation and invasion of non-small-celllung carcinoma by targeting WNT5A[J]. Cell Death and Disease, 2018, 9(2):189.

29.He X, Chen S Y, Yang Z, Zhang J, Wang W, Liu M Y, Niu Y, Wei X M, Li H M, Sun G G, Hu W N, Sun G H. miR-4317suooresses non-snall cell lung cancer (NSCLC)bytargeting fibroblast growth factor 9(FGF9)and cyclin D2(CCND2)[J]. Journal of Experimental and Clinical Cancer Research, 2018, 37(1):230.

30.Liu Y K, Zhanq Y N, Wu H D, Li Y F, Zhang Y, Liu M, Li X, Tang* H. miR-10a suppresses colorectal cancer metastasis by modulating the epithelial-to-mesenchymal transition and anoikis[J]. Cell Death and Disease, 2017, 8(4):e2739.

31.Liu Y K, Han S G, Li Y H, Liu Y, Zhang D, Li* Y F, Zhang* J H. miR-20a contributes to cisplatin-resistance and migration of ovarian cancer cell line OVCAR3[J]. Oncology Letters, 2017, 14(2):1780-1786.

32.Nagarajan D, Wang L, Zhao W, Han X. Trichostatin A inhibits radiation-induced epithelial-tomesenchymal transition in the alveolar epithelial cells[J]. Oncotarget, 2017, 8(60):101745-101759.

33.Zhao Y, He J, Sun G G, Hu W. miR-769-5p suppressed cell proliferation,migration and inwasion by targeting TGFBR1 in non-small cell lung carcinoma[J]. OncotargetYang Z, He J, Gao P. miR-769-5p suppressed cell proliferation, migration and invasion by targeting TGFBR1 in non-small cell lung carcinoma[J]. Oncotarget, 2017, 8(69):113558-113570.

34.Xu S, Tian S, Jiang C, Liu X, Zhang Z, Chen H, Zhang Y, Liu Y, Ma D. Hypermethylation of IFN-γ in oral cancer tissues[J]. Clinical Oral Investigations, 2017, 21(8):2535-2542.

35.Gan J H, Zhao Z Y, Liu J B, Cheng Q. Clinical evaluation of combination of dexmedetomidine and midazolam vs. dexmedetomidine alone for sedation during spinal anesthesia[J]. Saudi Journal of Biological Sciences, 2017, 24(8):1758-1762.

36.Zheng M, Zhou S, Shen Y, Wang L, Che R, Hu W, Li P. DNA methylation of METTL7A gene body regulates its transcriptional level in thyroid cancer[J]. Oncotarget, 2017, 8(21):34652-34660.

37.Zheng M, Hu W, Gao H, Sun S, Wang H, Yue Z, Zhu Y, Han X, Yang J, Zhou Y, Cai Y. Chaperonin containing TCP1 subunit 5 is a tumor associated antigen of non-small cell lung cancer[J]. Oncotarget, 2017, 8(38):64170-64179.

38.Zhao Y T, Yan J Y, Han X C, Niu F L, Zhang J H, Hu W N. Anti-proliferative effect of digoxin on breast cancer cells via inducing apoptosis[J]. European Review for Medical and Pharmacological Sciences, 2017, 21(24):5837-5842.

39.Zhang Y, Yan J Y, Wang L, Dai H, Li N, Hu W, Cai H F. HIF-1a Promotes Breast Cancer Cell MCF-7 Proliferationand Invasion Through Regulating miR-210[J]. Cancer Biotherapy and Radiopharmaceuticals, 2017, 32(8):297-301.

40.Yan J Y, Cai H F, Zhang J H, Zhang B, Li N, Hu W N. Treatment of breast cancer based on FOLFOX4 therapy for colon cancer: A case report[J]. Biomedical Research, 2017, 258-261.

41.Zhang J H, Zhang T, Gao S H, Wang K, Yang X Y, Mo F F, Yu N, An T, Li Y F, Hu J W, Jiang* G J. Mitofusin-2 is required for mouse oocyte meiotic maturation, 2016, 6(1):30970.

42.Zhang Y, Wang L, Li N, Dai H, Sun J, Cai H F. Downregulation of long non-coding RNA MALAT1 induces tumor progression of human breast cancer through regulating CCND1 expression[J]. Open Life Sciences, 2016, 11: 232–236.

43.Yan J Y, Zhang Y. The role of miR-222 and miR-298 in breast cancer drug resistance[J]. International Journal of Clinical and Experimental Pathology, 2016, 9(10):9931-9937.

44.Liu Y K, Guo S H, Wang L, Suzuki S, Sugimura H, Li Y F. Uterien Angiosarcoma :A Case Report and Literature Review [J]. International journal of Gynecological Pathology, 2016, 35(3):264-8.

45.Liu X, Guan Y, Xu S, Li Q, Sun Y, Han R, Jiang C. Early Predictors of Acute Kidney Injury:A Narrative Review [J]. Kidney Blood Pressure Research, 2016, 41(5):680-700.

46.Song H, Xiong H, Che J, Xi Q S, Huang L, Xiong H H.Gel-Based Chemical Cross-Linking Analysis of 20S Proteasome Subunit-Subunit Interactions in Brest Cancer [J]. J Huazhong University Science Technology Medical Science, 2016, 36(4):564-570.

47.Zhao L M, Sun G G, Han L N, Liu L H, Ren F Z, Li L, Ma M, Shan B E. P-Hydroxycinnamaldehyde Induces B16-F1 Mwlanoma cell Differentiation via the RhoA-MAPK Signaling pathway [J]. Cellular Physiolgy and Biochemistry, 2016, 38(6):2247-60.

48.Zhang J H, Zhang T, Gao S H, Wang K, Yang X Y, Mo F F, Na Yu, An T, Li Y F, Hu J W, Jiang G J. Mitofusin-2 is required for mouse oocyte meiotic maturation [J]. Scientific Reports, 2016 , 6:30970.

49. Wang Y, Liu Y, Li Y, Zhang J, Liu Y, Li Y, Deng Y, Wang S. Williams syndrome transcription factor is a target of pro-oncogenic Ser158 phosphorylation mediated by Ras-MAPK pathway in human breast cancer [J]. International Journal of Clinical and Experimental Pathology, 2016, 9(2), 1668-1675.

50.Liu Y, Wang S Q, Long Y H, Chen S, Li Y F, Zhang J H. KRASG12 mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway [J]. Oncotarget, 2016, 7(33):53153-53164.

51.Liu Y, Long Y H, Wang S Q, Li Y F, Zhang J H. Phosphorylation of H2A.XTyr39 positively regulates DNA damage response and is linked to cancer progression [J]. FEBS Journal, 2016, 283(24):4462-4473.

52.Xing L, Liu Z, Deng G, Wang H, Zhu Y, Shi P, Huo B, Li Y. Xanthogranulomatous prostattis with prostato-rectal fistula:a case report and revew of the literature[J]. Research and Repores in Urology, 2016, 8:165-168.

　　2)Scientific and technological achievements rewards

　　1. applied basic researches, Science and Technology Progress Award, 肿瘤分子诊疗关键技术研究及应用, Guogui Sun (First), Wanning Hu (Second), Yufeng Li (Third), Jinghua Zhang (Forth). Tangshan People’s Hospital, collaborating institutions: North China university of technology, the Fourth Hospital of Hebei Medical University and Tangshan worker Hospital

　　2. applied basic researches, other awards, 胸水VEGF、CEA、ADA和AFU联合测定对良恶性胸腔积液诊断价值的研究, Sugui Han(First), Tangshan People’s Hospital, collaborating institutions: Tangshan hospital of maternal and child health care and Tangshan infectious disease hospital

　　3. applied basic researches, other awards, 肿瘤可溶性抗原和金葡菌超抗原构建肿瘤疫苗的实验研究, Wanning Hu (First), Tangshan People’s Hospital, collaborating institutions: none

　　4. applied basic researches, other awards, Id1、Id3、VEGF、CerbB2、PCNA在乳腺癌中的表达及临床意义, Jinghua Zhang (First), Tangshan People’s Hospital, collaborating institutions: none

　　5. applied basic researches, other awards, PPN/MG61基因检测鉴别良恶性胸腔积液的研究, Wanning Hu (Third), Weidong Liu (Forth), Tangshan People’s Hospital, collaborating institutions: none

　　6. applied basic researches, other awards, 羟乙基淀粉在体外对正常人体细胞因子的影响, Wanning Hu (Second), Tangshan People’s Hospital, collaborating institutions: none

　　7. applied basic researches, other awards, 用ISO9001:2008标准研究医院资源管理, Wanning Hu (Second), Jinghua Zhang (Forth), Wenbo Yao (Fifth), Tangshan People’s Hospital, collaborating institutions: none

　　8. applied basic researches, other awards, DMBT1等基因在多种肿瘤的表达及与发生发展预后的关系, Guogui Sun (First), Tangshan People’s Hospital, collaborating institutions: Kai Ping Hospital and Tangshan worker Hospital

　　9. applied basic researches, the third of Provincial science and technology progress prize, 内镜技术治疗口腔颌面部良性肿物的临床研究及应用, Wenbo Yao (Third), Tangshan xiehe Hospital, collaborating institutions: Tangshan People’s Hospital

　　10. applied basic researches, other awards, PEG/PEJ在晚期胰头癌中的应用及其护理研究, Jinghua Zhang (Fifth), Tangshan People’s Hospital, collaborating institutions: none

　　11. applied basic researches, other awards, MnSOD等六种基因表达与六种肿瘤恶性表型形成干预的相关性研究, Wanning Hu (First), Guogui Sun (Second), the Fourth Hospital of Hebei Medical University, collaborating institutions: Tangshan People’s Hospital, Beijing military area command of the Chinese people's liberation army general hospital and Tangshan worker Hospital

　　12. applied basic researches, other awards, 岩舒对头颈鳞癌放化疗疗效及外周血中cyclinB2、wnt5a、Cdc6的影响, Wanning Hu (Third), Tangshan People’s Hospital, collaborating institutions: none.

　　3)Independent intellectual property rights

　　1. utility model patent, 防冻节水封闭型双瓮漏斗式厕所, ZL 2014 2 0327886.6, 2014/6/19

　　2. utility model patent, X线电子计算机断层扫描组织病理诊断机, ZL 2011 2 0203665.4, 2011/6/16

　　3. utility model patent, 医务人员专用防院感一次性擦手消毒巾, ZL 2011 2 0060583.9, 2011/3/10

　　4. utility model patent, 多功能微创小切口手术器械, ZL 2011 2 0061137. X, 2011/3/10

　　5. utility model patent, 一次性经皮穿刺活检, ZL 2009 2 0163502.0, 2009/7/3

　　6. utility model patent, 一次性多功能胸腹水引流器, ZL 2009 2 0163503.5, 2009/7/3

　　7. utility model patent, 电子静脉注射药物配伍禁忌检索仪, ZL 2009 2 0163501.6, 2009/7/3